Rad52 Promotes Postinvasion Steps of Meiotic Double-Strand-Break Repair
نویسندگان
چکیده
منابع مشابه
Two separable functions of Ctp1 in the early steps of meiotic DNA double-strand break repair
Meiotic programmed DNA double-strand break (DSB) repair is essential for crossing-over and viable gamete formation and requires removal of Spo11-oligonucleotide complexes from 5' ends (clipping) and their resection to generate invasive 3'-end single-stranded DNA (resection). Ctp1 (Com1, Sae2, CtIP homolog) acting with the Mre11-Rad50-Nbs1 (MRN) complex is required in both steps. We isolated mul...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2008
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2007.12.014